Multicompartmentalized polymersomes for selective encapsulation of biomacromolecules

Posted: 20 jan. 2011
Citation: Chem. Commun., 2011,47, 2862-2864

Authors: Zhikang Fu,a   Mirjam Andreasson Ochsner,a   Hans-Peter M. de Hoog,b   Nikodem Tomczak*a  and  Madhavan Nallani*ab  


Multicompartmentalized polymersomes are formed using block co-polymers PMOXA–PDMS–PMOXA and PS-PIAT, and are subsequently proven to be capable of selective encapsulation of biomacromolecules. This architecture mimics the compartmentalization found in cells and may serve as a simple, albeit robust, model system.