Career

We are currently offering the following positions:

ACM Biolabs was founded in Singapore in 2013 to develop its proprietary polymer-based delivery platform. Our lead asset, ACM-001, uses polymersomes to deliver SARS-CoV-2 beta variant antigen efficiently to key immune cells.

ACM will soon become a clinical stage biotech company utilizing its proprietary and non-immunogenic, inert delivery platform to deliver proteins, peptides, mRNA and oligonucleotides to revolutionize vaccines and therapies. Its subsidiary, ACM Biosciences, was founded 2020 in Basel, Switzerland. Clinical development, regulatory interactions and partnering will be coordinated out of our Basel offices.

We continue to build a world-class team of specialists.

Current positions in detail:

SGP-L-1001-22-03-J, 8 March 2022

RESEARCH ASSISTANT | JUNIOR SCIENTIST
(PRECLINICAL VACCINE DEVELOPMENT)

RESPONSIBILITIES

  • He or she will be responsible for designing and performing experiments to determine mechanism of action, in vivoimmunogenicity and vaccine efficacy. 
  • Candidate should be responsible, meticulous and thorough in the execution of experiments and the recording of methods and results
  • Candidate is expected to present their findings clearly, accurately, concisely and in a timely manner via PowerPoint presentations and formal reports. 

PROFESSIONAL EXPERIENCE/QUALIFICATIONS

The candidate should ideally possess the following skills and experience: 

  • Bachelor degree in life science or PhD in microbiology, immunology or related field
  • Minimum 3 years’ experience with mice is a must. Candidate should be proficient in various routes of administration (IM, SC, IV, IP, etc), anaesthesia, in-life blood collection and organ collection (LNs, spleen, etc). Knowledge of IN administration and BAL will be a plus.
  • Tissue dissociation, PBMC isolation, cell counting and cryopreservation.
  • Multicolour flow cytometry (>8 markers).
  • T cell analysis (phenotypic and functional characterisation).
  • ELISA (indirect; sandwich) to analyse biological fluids and cell culture supernatants.
  • Well-versed in the use of GraphPad Prism software and its statistical tools.
  • Knowledge of viral or cancer immunology.

Interested?
We look forward to receiving your application under kang@acmbiolabs.com


SGP-L-1002-22-04-S, 12 April 2022 

HEAD OF TECHNICAL DEVELOPMENT

THE POSITION

The Head of Technical Development is a member of the ACM Management Team. He/she is the strategic lead of ACM Biolabs’ polymer-based platform technology and CMC activities to support the advancement of the delivery technology and the pipeline development programs. He/she reports into the Chief Scientific Officer and will manage close to 6 scientists and technicians in the department in Singapore.

The Head of Technical Development has significant long ranging strategic impact and contributes to the major strategic goals of ACM:

  • Advancement of the polymer-based delivery platform in an integrated discovery and development paradigm
  • Responsible for drug substance and drug product related activities in support of all discovery assets at ACM Biolabs delivering upon strategy, timelines and financial targets.
  • The Head of Technical Development develops a network of relationships/partnerships with external partners to support supply of all preclinical research and development programs as well as manufacturing under GMP conditions for the clinical trials
  • Develops long-term strategy for the GMP supply chain internally or with selected CMDOs

KEY RESPONSIBILITIES

  • Enable scientific, strategic and operational excellence of the Technology Department
  • Be an engaged and participative member of the Management Team
  • Coordinates cross-functional efforts to meet short- and long-term project goals
  • Conducts high quality, innovative research to next generation targeted delivery within the approved strategy.
  • Develops and establishes scalable process that is transferable to a GMP manufacturing with Innovative solutions for novel process
  • Establishment of analytical methods with proper qualification and validation 
  • Selection and due diligence of CMOs and CROs, manage the relationship with selected external parties for efficient project delivery
  • Develops and delivers clear communications of program strategy, progress, and needs across the organization, articulating messages clearly and concisely adapted to the objectives and needs of the audience (verbal and written)
  • Coordinates two or more programs and project teams in parallel
  • Responsible for the delivery of Clinical materials and GMP material for ACM programs
  • Participates and/or coordinates national or international collaborations and strategic alliances
  • Recruits new staff, manages changes and reorientation of staff for efficient project delivery

PROFESSIONAL EXPERIENCE/QUALIFICATIONS

The candidate should ideally possess the following skills and experience: 

  • Demonstrated technology expertise in delivery technologies for various molecule classes (ideally nanoparticles or lipid complex process).
  • Significant experience in a Pharma or Biotech environment is required
  • Recognized by internal and external peers for scientific excellence, scale-up and manufacturing expertise
  • Proven track record of scientific excellence that has significantly impacted technical development of nanoparticle formulations and or biomolecules (Proteins, RNA and DNA)
  • Expertise in developing robust manufacturing process from lab scale to manufacturing scale with quality control expertise
  • Demonstrated ability to manage and mentor people; ability to provide support and guidance for career development for direct reports
  • Ability to present to senior management and at international forums
  • Well organized and excellent communication skills
  • Fluency in English is required.

EDUCATION

  • A Ph.D/MD/PharmD degree in pharmaceutical manufacturing technologies or a related field along with 5 years post degree experience is required
  • Job Level: Manager with direct reports

Working place: Singapore

Interested?
We look forward to receiving your application under kang@acmbiolabs.com